I'm in the middle of writing a review of the Nook, and I keep having to revise it. My biggest complaint is that the touchscreen is underutilized. The original design is a very basic menu system. The Nookdevs group also noted the shortcomings of the touchscreen menus, and they're doing something about it.
Meet the NookLauncher. It's a replacement for the 5 button launcher that originally came with the Nook. It's designed to let you add more buttons to launch apps and arrange the icons in any order desired.